Facilities

The Industrial BioDevelopment Laboratory is located at the MaRS Centre in the Toronto Medical Discovery Tower. It consists of a cell culture suite, the Pall Life Sciences Pilot Plant for downstream purification, GLP testing laboratories and associated supporting infrastructure, including:

• Washing and sterilizing facility
• -80 °C freezers
• Cold room
• Incubator Room

Process Equipment

• New Brunswick Scientific and Infors Bioreactors (0.5 - 40 L)
• Cobe 2991Cell Processor
• Beckman Coulter High Capacity High Speed and Ultra- Centrifuges
• Pall Minimate Ultrafiltration System
• Pall Centramate Ultrafiltration System
• Filtration
• Pall PKL6 Pilot-Scale Chromatography System (largest column 9 cm dia x 30 cm long)
• FTS Systems Freeze Dryer

Organic Synthesis Equipment (for up 10 L batch size)

• Buchi Distillation Unit
• Buchi Rotary Evaporator
• Vacuum Oven

Laboratory Equipment

• Thermo Electron Finnigan Surveyor Plus HPLC System
• Thermo Electron Finnigan LTQ Linear Ion Trap Mass Spectrometer
• Thermo Electron UV-Vis Spectrophotometer
• Thermo Electron KingFisher Dynabeads
• Beckman Coulter ProteomeLab PF 2D Protein Fractionation System
• Beckman Coulter ProteomeLab PA800 Protein Characterization System
• Beckman Coulter Vi-Cell XR Cell Viability AnalyzerBio-Rad Electrophoresis Equipment